Dynamics of Bacterial Quorum Sensing in Microfluidic Devices
نویسنده
چکیده
Figure 1: E. coli cells engineered with the luxI/luxR system and the microfluidic device setup in our experiments [4]. C6-HSL is a specific type of AHL. Quorum sensing is an essential communication mechanism in bacteria. By transmitting small molecules to each other, bacteria can sense their own population and respond accordingly. Coupling such mechanisms with synthetic biology can lead to a wide range of potential applications, including microbial detection of heavy metals [1]. Although many quorum sensing mechanisms have been characterized at the molecular level, variations in population-level responses are not well understood.
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